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Molecular pharmacological aspects of histamine receptors
R Leurs1, M J Smit, H Timmerman
1Leiden/Amsterdam Center for Drug Research, Department of Pharmacochemistry, Vrije, Universiteit, The Netherlands.
Pharmacology & Therapeutics
|June 1, 1995
Abstract:
In this article, we review the recent developments in the field of histamine research. Besides the description of pharmacological tools for the H1, H2 and H3 receptor, specific attention is paid to both the molecular aspects of the receptor proteins, including the recent cloning of the receptor genes, and their respective signal transduction mechanisms.