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Bacteremia with nontyphi Salmonella and therapeutic implication
C B Ryu1, M L Lee, E K Namgoong
1Department of Internal Medicine, Clinical Pathology, Soonchunhyang University Hospital, Seoul, Korea.
The Korean Journal of Internal Medicine
|July 1, 1995
Summary
Nontyphi Salmonella bacteremia is increasing, particularly in those with underlying conditions. This study analyzed 30 cases, revealing a 13.3% fatality rate and varied clinical presentations, highlighting the need for clinical evaluation.
Area of Science:
- Infectious Diseases
- Clinical Microbiology
- Epidemiology
Background:
- Nontyphi Salmonella bacteremia incidence is rising globally, especially in immunocompromised individuals.
- This contrasts with a declining trend of Salmonella typhi infections in some regions, like Korea.
Purpose of the Study:
- To clinically evaluate patients diagnosed with nontyphi Salmonella bacteremia.
- To understand the epidemiological and clinical characteristics of nontyphi Salmonella bacteremia.
Main Methods:
- A retrospective study of 30 nontyphi Salmonella bacteremia cases admitted between 1987 and 1993.
- Analysis included age distribution, underlying diseases, clinical presentation, and patient outcomes.
Main Results:
- The study included 30 patients, with a male to female ratio of 3:2.
- Vulnerable age groups (under 2 years and over 55 years) were represented.
- 13.3% (4 out of 30) of patients experienced fatal outcomes.
Conclusions:
- Nontyphi Salmonella bacteremia presents diverse clinical features and a significant mortality rate.
- The findings underscore the importance of recognizing and managing nontyphi Salmonella bacteremia, especially in vulnerable populations.