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Jaccoud's arthropathy. A case report and necropsy study

F L Girgis, A W Popple, F E Bruckner

    Annals of the Rheumatic Diseases
    |December 1, 1978
    PubMed
    Summary

    Jaccoud's arthropathy, a rare condition causing painless joint deformities, was observed in a woman after rheumatic fever. Histological analysis revealed joint capsule thickening and degenerative changes, not significant synovial pathology.

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    Area of Science:

    • Rheumatology
    • Pathology
    • Medical case study

    Background:

    • Jaccoud's arthropathy is a rare, non-erosive arthropathy characterized by reversible joint deformities.
    • It is often associated with rheumatic fever and systemic lupus erythematosus.
    • The condition typically affects the metacarpophalangeal and proximal interphalangeal joints.

    Observation:

    • A case of Jaccoud's arthropathy is presented in a 59-year-old woman with a history of four rheumatic fever attacks.
    • The patient exhibited painless, correctable ulnar deviation of the metacarpophalangeal joints.
    • Radiological examination did not reveal the characteristic hook lesions, and there was no clinical evidence of rheumatoid arthritis.

    Findings:

    • Histopathological examination of three finger joints obtained post-mortem showed fibrous thickening of the joint capsule.
    • Secondary degenerative changes were noted, likely due to chronic joint deformity.
    • No significant synovial pathology was identified.

    Implications:

    • This case highlights that hook lesions may not be essential for diagnosing Jaccoud's arthropathy.
    • The pathological findings contribute to understanding the underlying structural changes in this rare condition.
    • Further research into the pathogenesis and diagnostic criteria for Jaccoud's arthropathy is warranted.

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