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Cathepsin D--a main proteolytic enzyme of the bovine vitreous
1Department of Biochemistry, Medical Academy of Białystok.
Roczniki Akademii Medycznej W Bialymstoku (1995)
|January 1, 1994
Abstract:
It was found that the bovine vitreous contains a proteolytic enzyme which demonstrates characteristic features of cathepsin D. It acts in acidic pH, actively digests denatured protein substrates and demonstrates a high susceptibility on the inhibitory action of pepstatin. It is localized in liquid part of the bovine vitreous. A role of this enzyme in physiology and pathology of the eye is discussed.