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The preferential dopamine D3 receptor ligand, (+)-UH232, is a partial agonist

N Griffon1, C Pilon, J C Schwartz

  • 1Unité de Neurobiologie et Pharmacologie de l'INSERM, Centre Paul Broca, Paris, France.

European Journal of Pharmacology
|August 25, 1995
PubMed
Summary

(+)-UH 232 acts as a partial agonist at dopamine D3 receptors, stimulating cell growth (mitogenesis) and inhibiting cAMP production. This selective D3 receptor ligand shows partial agonist activity with an intrinsic activity of 0.2-0.4.

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