Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Anaesthesia and autologous transfusion

B Borghi1, A Bassi, M Grazia

  • 1Anaesthesia and Intensive Care Unit, Rizzoli Orthopaedic Institute, Bologna, Italy.

The International Journal of Artificial Organs
|March 1, 1995
PubMed
Summary

Anesthesiologists coordinate blood-saving techniques for joint replacement surgery. Indobufen prophylaxis significantly reduced the need for homologous blood transfusions in 980 patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Addressing challenges along the 'access cascade' for new TB regimens.

IJTLD open·2026
Same author

Enhancing collaboration between national TB programmes and researchers.

IJTLD open·2026
Same author

Large Region of Homozygous (ROH) Identified in Indian Patients with Autosomal Recessive Limb-Girdle Muscular Dystrophy with p.Thr182Pro Variant in <i>SGCB</i> Gene.

Human mutation·2025
Same author

Tufted hair at birth: A previously undescribed peculiar sign of trichothiodystrophy.

Journal of the European Academy of Dermatology and Venereology : JEADV·2023
Same author

Large field of view aberrations correction with deformable lenses and multi conjugate adaptive optics.

Journal of biophotonics·2023
Same author

Somatic yolk sac differentiation in tumors of the gynecologic tract: A report of two cases and review of the literature.

Gynecologic oncology reports·2022

Area of Science:

  • Anesthesiology
  • Orthopedic Surgery
  • Transfusion Medicine

Background:

  • Anesthesiologists are crucial for managing blood conservation strategies.
  • Effective transfusion therapy requires pre-operative planning, intraoperative salvage estimation, and post-operative infusion management.
  • Maintaining hemodilution is key during the initial three days post-surgery.

Purpose of the Study:

  • To evaluate the incidence of homologous transfusions in patients undergoing total joint replacement.
  • To identify factors influencing the need for blood transfusions in this patient cohort.

Main Methods:

  • A retrospective analysis of 980 patients undergoing total joint replacement (hips and knees) between January 1992 and June 1994.
  • Data collected included basal hemoglobin, surgical procedures, and type of antithromboembolic prophylaxis used.

Related Experiment Videos

  • Statistical analysis to determine factors influencing transfusion requirements.

    • Main Results:

    • Overall, 6.3% of patients received homologous transfusions.
    • Factors negatively influencing transfusion need included female sex, coronary heart disease (p=0.005), and surgery length.
    • Indobufen prophylaxis showed a significantly lower incidence of transfusion (p=0.0001) compared to calcium heparin or low molecular weight heparin.

    Conclusions:

    • The anesthesiologist's role is central in optimizing blood management strategies.
    • Antithromboembolic prophylaxis choice, specifically indobufen, can significantly reduce homologous transfusion rates in joint replacement surgery.
    • Patient-specific factors like comorbidities and surgical duration impact transfusion needs.