Related Experiment Video
Updated: Jul 18, 2026

"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection
Published on: February 19, 2019
Serum markers for connective tissue turnover in patients with chronic hepatitis B and chronic hepatitis C: a
Y Murawaki1, Y Ikuta, Y Nishimura
1Second Department of Internal Medicine, Tottori University School of Medicine, Yonago, Japan.
Background/Aims:
Clinical and pathological differences between chronic hepatitis B and chronic hepatitis C have now been established.
Methods:
To compare hepatic connective tissue metabolism in chronic hepatitis B and C, we determined serum levels of prolyl 4-hydroxylase beta-subunit, procollagen III aminoterminal peptide, type IV collagen 7S domain, the central helix region of type IV collagen, tissue inhibitor of metalloproteinase, and hyaluronan in 55 patients with chronic hepatitis B and 83 patients with chronic hepatitis C.
Results:
There were no significant differences in the above markers for connective tissue turnover between the chronic hepatitis B group and the chronic hepatitis C group.
Conclusions:
These results suggest that the accelerated connective tissue metabolism observed in chronic viral hepatitis is independent of the causative virus.
More Related Videos
Related Concept Videos
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
Hepatitis
Viral Hepatitis I: Introduction
Cirrhosis I: Introduction
Cirrhosis II: Pathophysiology

