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Related Experiment Videos

Myocardial tagging with B1 insensitive adiabatic DANTE inversion sequences

N V Tsekos1, M Garwood, H Merkle

  • 1Center for Magnetic Resonance Research, University of Minnesota Medical School, Minneapolis 55455, USA.

Magnetic Resonance in Medicine
|September 1, 1995
PubMed
Summary

A novel cardiac MRI tagging technique using DANTE inversion sequences creates uniform myocardial contrast despite B1 field variations. This method accurately tracks heart wall motion through detailed grid deformation analysis.

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Area of Science:

  • Cardiovascular Magnetic Resonance Imaging
  • Biomedical Engineering
  • Medical Physics

Background:

  • Cardiac MRI tagging is crucial for assessing myocardial function.
  • B1 field inhomogeneities can degrade tag contrast and accuracy.
  • Existing tagging methods struggle with consistent performance under varying magnetic field conditions.

Purpose of the Study:

  • To introduce and validate a new DANTE-based inversion sequence for cardiac MRI tagging.
  • To achieve uniform myocardial tag contrast resistant to B1 inhomogeneities.
  • To demonstrate the technique's capability in tracking cardiac wall motion.

Main Methods:

  • Development of an adiabatic delays alternating with mutations for tailored excitation (DANTE) inversion pulse sequence.

Related Experiment Videos

  • Application of the pulse sequence in phantom and animal heart tagging studies.
  • Utilized a surface coil for both MRI transmission and signal reception.

    • Main Results:

    • Demonstrated uniform tag contrast across the myocardial wall despite a sixfold variation in B1 magnitude.
    • Achieved sharp tagging profiles for precise delineation of myocardial motion.
    • Successfully tracked cardiac wall motion via deformation of a fine rectangular tagging grid throughout the cardiac cycle.

    Conclusions:

    • The DANTE-based tagging technique provides robust and uniform myocardial contrast.
    • This method overcomes limitations posed by B1 inhomogeneities in cardiac MRI.
    • The technique enables accurate assessment of cardiac mechanics and wall motion.