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Glomerulonephritis associated with permanent pacemaker endocarditis

E Barnes1, A Frankel, E A Brown

  • 1Department of Nephrology, Charing Cross Hospital, London, UK.

American Journal of Nephrology
|January 1, 1995
PubMed
Summary
This summary is machine-generated.

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Pacemaker endocarditis, an infection of the heart lining, can cause fever and kidney failure in patients with cardiac pacemakers. Early diagnosis and treatment are crucial for recovery, though complications can be severe.

Area of Science:

  • Cardiology
  • Nephrology
  • Infectious Diseases

Background:

  • Transvenous cardiac pacemakers are essential devices for managing cardiac arrhythmias.
  • Infection of cardiac devices, such as pacemakers, is a serious complication.
  • Pyrexia of unknown origin and renal failure can be indicators of underlying systemic illness.

Observation:

  • Two patients with permanent transvenous cardiac pacemakers presented with pyrexia of unknown origin and renal failure.
  • Extensive investigations revealed pacemaker endocarditis in both individuals.
  • Renal biopsy in one patient showed glomerulonephritis consistent with the infection.

Findings:

  • Pacemaker endocarditis was diagnosed in both patients.
  • Both patients required surgical intervention (thoracotomy) for pacemaker removal and antibiotic therapy.

Related Experiment Videos

  • One patient experienced significant recovery of renal function, while the other unfortunately succumbed.

    • Implications:

    • This case series highlights the importance of considering pacemaker endocarditis in patients with pacemakers presenting with unexplained fever and renal dysfunction.
    • The diagnostic challenges associated with pacemaker endocarditis are emphasized.
    • Vigilance for these uncommon but serious complications is essential for timely management and improved patient outcomes.