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Galactorrhea caused by esophagitis

D B Turton1, K M Shakir

  • 1Department of Radiology, National Naval Medical Center, Bethesda, MD 20889-5600, USA.

American Journal of Obstetrics and Gynecology
|November 1, 1995
PubMed
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A case study reveals painful esophagitis as a novel cause of galactorrhea (milk production). Treatment of the esophageal inflammation resolved the condition, suggesting a link to chest wall stimulation mechanisms.

Area of Science:

  • Endocrinology
  • Gastroenterology
  • Reproductive Medicine

Background:

  • Galactorrhea, the inappropriate production of milk, is typically associated with hormonal imbalances or certain medications.
  • Unusual etiologies for galactorrhea require thorough investigation to identify underlying causes.
  • Esophagitis, inflammation of the esophagus, is not commonly recognized as a cause of galactorrhea.

Observation:

  • This report details a unique case of galactorrhea directly linked to symptomatic, painful esophagitis.
  • The patient experienced significant discomfort due to esophageal inflammation.

Findings:

  • The galactorrhea resolved completely and promptly following targeted treatment of the esophagitis.
  • This suggests a physiological connection between esophageal inflammation and milk production.

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Implications:

  • The mechanism may involve neural reflex pathways similar to those triggered by chest wall stimulation.
  • Clinicians should consider esophagitis as a potential, albeit rare, cause when evaluating patients with unexplained galactorrhea.
  • Further research into neuro-gastrointestinal-endocrine reflexes could elucidate this association.