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[Psychopharmacological study of two 3-arylsulfonyl 4-hydroxy-coumarines]
S L Cheav1, S Kirkiacharian, R Kurkjian
1Laboratoires de Neuropharmacologie, UFR de Pharmacie, Tours.
Annales Pharmaceutiques Francaises
|January 1, 1995
Abstract:
The pharmacological study of 3-(4-chlorophenylsulfonyl) 4-hydroxy-7-methoxy- coumarine and 3-(4-methylphenylsulfonyl) 4-hydroxy-7-methoxy-coumarine shows that these derivatives present low sedative effects on the central nervous system, particularly due to their actions upon temperature and motility, more accentuated for the chloro-substituted derivative.