[The hierarchy of complexes and compact structures of trivaline with nucleic acids. II. Interaction of trivaline with...

It has been shown by equilibrium dialysis that at a poly(U) concentration above the "critical" one, the complete polymer saturation with trivaline reaches approximately 0.7, i.e., in these conditions the peptide dimer occupied on poly(U) a site of three bases in length. It has been shown by flow linear dichroism that trivaline beta-dimers preferentially binding with the single-stranded polymer rather than with the double-stranded one. It has been shown by electron microscopy that "the highest" compact structure of trivaline-poly(C) consists of dozens of "biduplex" structures. Beginning with a dimer trivaline-poly(U) complex, we proposed a schematic model for other complexes and compact structures of these molecules.