Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Antiepileptic drugs: future development

¹Wyeth-Ayerst Research, Clinical Research & Development, Philadelphia, PA 19101-8299.

Epilepsy Research. Supplement

|January 1, 1993

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Consensus on Subdomains and Measures of Relevance to Affective and Social Cognition Research on Bipolar Disorder (CAS-BD); Outcomes and Recommendations From an International Society for Bipolar Disorders Targeting Cognition Taskforce Study.

Bipolar disorders·2026

Same author

An investigation of the clinical impact and therapeutic relevance of a DNA damage immune response (DDIR) signature in patients with advanced gastroesophageal adenocarcinoma.

ESMO open·2024

Same author

The use of faecal microbiota transplant as treatment for recurrent or refractory Clostridioides difficile infection and other potential indications: second edition of joint British Society of Gastroenterology (BSG) and Healthcare Infection Society (HIS) guidelines.

The Journal of hospital infection·2024

Same author

Clinical characteristics associated with the discrepancy between subjective and objective cognitive impairment in depression.

Journal of affective disorders·2019

Same author

Assessing and addressing cognitive impairment in bipolar disorder: the International Society for Bipolar Disorders Targeting Cognition Task Force recommendations for clinicians.

Bipolar disorders·2018

Same author

Methodological recommendations for cognition trials in bipolar disorder by the International Society for Bipolar Disorders Targeting Cognition Task Force.

Bipolar disorders·2017

Same journal

Functional expression of recombinant GABAA receptor channels in L929 fibroblasts.

Epilepsy research. Supplement·1996

See all related articles

New drug development for seizure disorders is advancing rapidly. Novel therapeutic compounds offer a promising future for treating epilepsy patients with more effective approaches.

Area of Science:

Neuroscience
Pharmacology
Drug Discovery

Background:

Epilepsy treatment has historically relied on serendipitous discoveries and broad screening.
The field is transitioning towards more sophisticated, rational drug design methodologies.

Purpose of the Study:

To highlight the paradigm shift in developing new antiepileptic drugs.
To emphasize the potential impact of novel compounds on epilepsy treatment.

Main Methods:

Review of historical and current trends in antiepileptic drug development.
Analysis of the shift from serendipity and screening to rational drug design.

Main Results:

The development of antiepileptic drugs (AEDs) has evolved significantly.

Related Experiment Videos

Current approaches focus on targeted mechanisms for greater efficacy and safety.

Conclusions:

The field of epilepsy treatment is entering a new era with advanced drug development.
Novel antiepileptic compounds are poised to revolutionize patient care and outcomes.