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[Hepatitis C: from pathogenesis to treatment]

J Delarive1, J P Berger

  • 1Hôpital du Samaritain, Vevey.

Schweizerische Rundschau Fur Medizin Praxis = Revue Suisse De Medecine Praxis
|November 9, 1993
PubMed
Summary
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Hepatitis C virus (HCV), a Flaviviridae family member, is a primary cause of non-A, non-B hepatitis. This article details the diagnosis, progression, and treatment of acute hepatitis C.

Area of Science:

  • Virology
  • Hepatology

Context:

  • Hepatitis C virus (HCV) is a significant cause of non-A, non-B hepatitis.
  • Antibodies against HCV are detected in 60-100% of post-transfusion non-A, non-B hepatitis patients.
  • The potential involvement of a second virus in non-A, non-B hepatitis remains under investigation.

Purpose:

  • To present the diagnosis of Hepatitis C virus infection.
  • To outline the clinical course of Hepatitis C.
  • To describe the treatment strategies for Hepatitis C.

Summary:

  • Hepatitis C virus (HCV), belonging to the Flaviviridae family, is implicated in most cases of non-A, non-B hepatitis.
  • Serological evidence confirms persistent HCV antibodies in a high percentage of transfusion-associated non-A, non-B hepatitis.

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  • While HCV is a common cause of sporadic acute hepatitis, the existence of a second causative agent cannot be ruled out.

    • Impact:

    • Provides essential information for diagnosing and managing Hepatitis C.
    • Contributes to understanding the epidemiology of non-A, non-B hepatitis.
    • Informs clinical practice regarding the treatment of acute hepatitis C.