Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Mechanically sensitive, nonselective cation channels

X C Yang1, F Sachs

  • 1Division of Biology 156-29, California Institute of Technology, Pasadena 91125.

EXS
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association between workplace health promotion service utilisation and depressive symptoms among workers: a nationwide survey.

Public health·2024
Same author

[Impact of NLR on atrial fibrillation recurrence after radiofrequency ablation in atrial fibrillation patients combined with heart failure].

Zhonghua xin xue guan bing za zhi·2022
Same author

[Metagenomic data-analysis reveals enrichment of lipopolysaccharide synthesis in the gut microbiota of atrial fibrillation patients].

Zhonghua xin xue guan bing za zhi·2022
Same author

[The effect of peripheral blood cell score on the prognosis of multiple myeloma patients treated with bortezomib].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi·2020
Same author

[Assessment of mortality burden and economic loss attributed to long-term PM(2.5) exposure in the Beijing-Tianjin-Hebei area].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi·2020
Same author

[Efficacy comparison of primary percutaneous coronary intervention by drug-coated balloon angioplasty or drug-eluting stenting in acute myocardial infarction patients with de novo coronary lesions].

Zhonghua xin xue guan bing za zhi·2020
Same journal

Forensic toxicology.

EXS·2010
Same journal

Biological warfare agents.

EXS·2010
Same journal

Chemical warfare agents.

EXS·2010
Same journal

Drugs of abuse: management of intoxication and antidotes.

EXS·2010
Same journal

Biological testing for drugs of abuse.

EXS·2010
Same journal

Inhalation toxicology.

EXS·2010
See all related articles

Mechanically sensitive channels (MSCs) are vital cell components that detect membrane tension. These universal transducers play key roles in various cellular processes across plants and animals.

Area of Science:

  • Cell Biology
  • Biophysics

Background:

  • Mechanically sensitive channels (MSCs) are present in all cell types.
  • They are crucial for sensing mechanical forces like membrane tension, osmotic gradients, and shear stress.

Purpose of the Study:

  • To review the distribution, biophysical properties, and functions of mechanically sensitive channels.
  • To highlight their role as primary mechanotransducers in cellular processes.

Main Methods:

  • Literature review of existing research on mechanically sensitive channels.
  • Analysis of biophysical properties including ion selectivity and density.

Main Results:

  • MSCs are cation-selective, K+-selective, or anion-selective.
  • They are found at densities of 0.2-5 per square micron.

Related Experiment Videos

  • MSCs respond to membrane tension, voltage, and ligands.

    • Conclusions:

    • The universal presence and properties of MSCs establish them as essential mechanotransducers.
    • They are fundamental to a wide array of cellular functions in both plants and animals.