How neurotransmitters affect axoplasmic transport?
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T Takenaka1, T Kawakami, Y Bandou
1Department of Physiology, Yokohama City University, Japan.
The Japanese Journal of Physiology
|January 1, 1993
Abstract:
The effects of acetylcholine (ACh) and adrenaline on fast axoplasmic transport of cultured superior cervical ganglion cells were analyzed with a computer-assisted video-enhanced differential interference contrast microscopic system. ACh suppressed the transport reversibly in both anterograde and retrograde directions, and adrenaline increased the transport reversibly. These effects are related to the amount of c-AMP. This amount of c-AMP in connection with neurotransmitters controls the axoplasmic transport, which in turn is related to the activity of the neuron.