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Benign prostatic hyperplasia: value of MR imaging for determining histologic type
J Ishida1, K Sugimura, H Okizuka
1Department of Radiology, Shimane Medical University, Enya Izumo, Japan.
Radiology
|February 1, 1994
Summary
Magnetic resonance (MR) imaging accurately distinguishes between stromal and nonstromal benign prostatic hyperplasia (BPH). This noninvasive technique aids in selecting appropriate pharmacotherapy for BPH management.
Area of Science:
- Radiology
- Urology
- Medical Imaging
Background:
- Benign prostatic hyperplasia (BPH) is a common condition in aging men.
- Histologic classification of BPH influences treatment decisions.
- Accurate noninvasive methods for BPH subtyping are needed.
Purpose of the Study:
- To evaluate the diagnostic value of magnetic resonance (MR) imaging for differentiating histologic subtypes of benign prostatic hyperplasia (BPH).
- To determine if MR imaging can reliably classify BPH as stromal or nonstromal.
Main Methods:
- MR imaging was performed on 33 patients with BPH using unenhanced and gadolinium-enhanced T1- and T2-weighted sequences at 1.5 T.
- Histologic classification criteria included nodule characteristics, presence of a surgical capsule, and inner gland to total gland volume ratio.
- Image analysis focused on identifying specific features indicative of stromal or nonstromal hyperplasia.
Main Results:
- MR imaging achieved 94% accuracy in classifying BPH subtypes.
- Nonstromal hyperplasia was correctly identified in 23 out of 24 patients.
- Stromal hyperplasia was correctly identified in 8 out of 9 patients, with characteristic nodular lesions and surgical capsules observed.
Conclusions:
- MR imaging is a valuable tool for the accurate histologic assessment of benign prostatic hyperplasia.
- This imaging modality can assist clinicians in choosing the most effective pharmacotherapy for BPH based on its subtype.