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Amylase-producing Bence Jones multiple myeloma with pancreatitis-like symptoms
J Lopez1, C Ulibarrena, P Gonzalez-Porque
1Department of Hematology, Hospital Ramón y Cajal, Madrid, Spain.
Acta Haematologica
|January 1, 1993
Abstract:
Amylase-producing tumors are mainly adenocarcinomas and, in rare instances, multiple myelomas. We describe here a first case of amylase-producing Bence Jones type myeloma with pancreatitis-like symptoms and the second in a Caucasian patient. The finding of salivary-type hyperamylasemia in a 72-year-old female with a possible pancreatitis made us suspect the diagnosis. Amylase production was observed in bone marrow cultures in which 96% of cellularity was composed of plasmablasts. Serum amylase level decreased when chemotherapy was given.