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Biochemical characterization of three non-lineage antigens defined by workshop antibodies
1International Laboratory for Research on Animal Diseases, Nairobi, Kenya.
Monoclonal antibodies (MAbs) from three temporary clusters recognized antigens expressed on platelets and a wide variety of other tissues. To confirm the clustering of the mAbs, we biochemically characterized the antigens recognized by each cluster. TC9 (BoCD44) contained mAbs to a 95 kDa ruminant antigen, homologous to human CD44. TC11 (BoWC9) defined a 25 kDa antigen and TC7 (BoWC11) defined an antigen composed of two subunits of 49 and 79 kDa.
Monoclonal antibodies (MAbs) from three temporary clusters recognized antigens expressed on platelets and a wide variety of other tissues. To confirm the clustering of the mAbs, we biochemically characterized the antigens recognized by each cluster. TC9 (BoCD44) contained mAbs to a 95 kDa ruminant antigen, homologous to human CD44. TC11 (BoWC9) defined a 25 kDa antigen and TC7 (BoWC11) defined an antigen composed of two subunits of 49 and 79 kDa.