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[Microwave hyperthermia for benign prostatic hyperplasia]

W J Bai1

  • 1People's Hospital, Beijing Medical University.

Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery]
|June 1, 1993
PubMed
Summary
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Transurethral microwave therapy effectively improved symptoms for many benign prostatic hyperplasia (BPH) patients. This minimally invasive treatment offered subjective relief and improved urinary flow in a significant number of men.

Area of Science:

  • Urology
  • Minimally Invasive Therapies
  • Thermal Ablation

Context:

  • Benign prostatic hyperplasia (BPH) is a common condition in aging men, causing lower urinary tract symptoms.
  • Transurethral therapies are standard treatments, but novel approaches are sought to improve efficacy and reduce side effects.

Purpose:

  • To evaluate the efficacy and safety of 915 MHz transurethral microwave thermal therapy for benign prostatic hyperplasia (BPH).

Summary:

  • 312 BPH patients received a single 60-minute session of 915 MHz transurethral microwave thermal therapy, achieving prostate temperatures of 43-45°C.
  • Six-month follow-up revealed subjective improvement in 70.1% of patients, with 37.0% showing increased flow rate and 43.0% experiencing decreased residual urine.
  • Failure cases (32) were attributed to factors including median lobe hyperplasia and comorbidities. In the acute retention group (39 patients), 21 had catheters removed within 2-7 weeks. Side effects (27 patients) included hematuria, fever, and acute retention, with rapid recovery.

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Impact:

  • This study demonstrates the potential of transurethral microwave thermal therapy as a viable treatment option for BPH, offering symptomatic relief and functional improvement.
  • The findings support further investigation into optimizing this minimally invasive technique for BPH management.
  • Understanding failure modes and side effect profiles aids in patient selection and clinical application.