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Prostate-specific antigen decline after casodex withdrawal: evidence for an antiandrogen withdrawal syndrome
1Department of Medicine, University of California, San Francisco.
Urology
|March 1, 1994
Abstract
Objective:
To evaluate the relationship between antiandrogen withdrawal and change in prostate-specific antigen (PSA) when the antiandrogen in question is other than flutamide.
Methods:
Presented is a case of a patient in whom the antiandrogen casodex was discontinued after clinical progression despite combined androgen blockade.
Results:
A transient decline in serum PSA was observed after casodex withdrawal.
Conclusions:
The relationship between antiandrogen withdrawal and a change in PSA may be a general phenomenon, not unique to flutamide.