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Related Experiment Videos

Hydroxyapatite orbital implants. Scanning with technetium-99m MDP

L M Numerow1, R Kloiber, R J Mitchell

  • 1Department of Radiological Sciences and Diagnostic Imaging, Foothills Hospital, Calgary, Alberta, Canada.

Clinical Nuclear Medicine
|January 1, 1994
PubMed
Summary
This summary is machine-generated.

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Assessing orbital implant vascularization using Tc-99m methylene diphosphonate scans reveals that planar imaging is superior to SPECT. Uniform radiophosphonate deposition, not just intensity, best indicates complete vascular ingrowth in hydroxyapatite spheres.

Area of Science:

  • Ophthalmology
  • Biomaterials Science
  • Nuclear Medicine

Background:

  • Porous hydroxyapatite spheres are used for orbital implantation due to tissue integration.
  • Vascularization of the implant is crucial before attaching a prosthesis via a central motility hole.
  • Drilling the motility hole in an avascular implant risks infection.

Purpose of the Study:

  • To evaluate the efficacy of radionuclide scanning with Tc-99m methylene diphosphonate for assessing vascular ingrowth in porous hydroxyapatite orbital implants.
  • To compare planar imaging and SPECT for defining complete implant vascularization.

Main Methods:

  • Tc-99m methylene diphosphonate radionuclide scanning was performed on 15 patients with hydroxyapatite orbital implants.
  • Scans were conducted 6 months post-insertion to assess vascular ingrowth.

Related Experiment Videos

  • Planar imaging and SPECT were utilized to analyze radiophosphonate deposition within the implants.

    • Main Results:

    • Complete vascularization of hydroxyapatite implants is better visualized using planar imaging compared to SPECT.
    • The uniformity of radiophosphonate activity within the implant is a more significant indicator of vascularization than relative intensity.
    • Tc-99m methylene diphosphonate deposition accurately parallels implant vascularization.

    Conclusions:

    • Planar radionuclide imaging is the preferred method for assessing vascularization of porous hydroxyapatite orbital implants.
    • Uniform radiophosphonate uptake is a key indicator for complete vascular ingrowth, essential for successful prosthetic eye coupling.
    • Tc-99m methylene diphosphonate scanning provides a reliable method to monitor implant integration and readiness for prosthesis attachment.