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The septum pellucidum and spatial ability of children with optic nerve hypoplasia
M Groenveld1, K R Pohl, H Espezel
1Newcomen Centre, Guy's Hospital, London.
Abstract:
Animal studies suggest that spatial skills are dependent on an intact septum pellucidum. This theory was tested by comparing patients who were visually impaired due to bilateral optic nerve hypoplasia: 13 with a septum pellucidum were compared with six children without a septum pellucidum. There was no difference in spatial ability. The finding of an absent septum pellucidum may only indicate the timing of a congenital brain insult, and it cannot be used to predict specific clinical, neuroendocrinological, cognitive or spatial abnormalities.
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