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[Geophagia sideropenica]

C Hadnagy, S Andreicut, P Binder

    Folia Haematologica (Leipzig, Germany : 1928)
    |January 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Two cases of geophagia, a form of anemia, were treated successfully with iron therapy. This suggests routine iron screening for blood donors may prevent geophagia.

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    Area of Science:

    • Hematology
    • Nutritional Medicine
    • Psychiatry

    Background:

    • Geophagia, the compulsive consumption of earth or soil-like substances, is often linked to nutritional deficiencies, particularly iron deficiency anemia.
    • Two cases involving a mother and daughter presenting with geophagia and concurrent anemia are detailed.

    Observation:

    • Both individuals exhibited moderate anemia and significant iron deficiency prior to the onset of geophagia.
    • Despite being regular blood donors, their iron levels were critically low, suggesting a pre-existing deficiency.
    • The geophagia symptoms resolved rapidly following intravenous iron supplementation, preceding significant hematological improvements.

    Findings:

    • Intravenous iron therapy (Ferrlecit) effectively resolved geophagia in both patients.

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  • Normalization of serum iron, erythrocyte count, hemoglobin, and hematocrit levels was observed post-treatment.
  • Electroencephalogram (EEG) abnormalities were noted in both cases, potentially influenced by iron repletion therapy.

    • Implications:

    • Routine serum iron level assessment in blood donors is recommended to identify at-risk individuals.
    • Proactive iron supplementation for blood donors could be a strategy to prevent geophagia and associated health issues.
    • Further research into the neurophysiological effects of iron deficiency and repletion in geophagia is warranted.