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Cutaneous malacoplakia

B Sarkell1, M Dannenberg, W K Blaylock

  • 1Department of Dermatology, Medical College of Virginia, Richmond.

Journal of the American Academy of Dermatology
|May 1, 1994
PubMed
Summary
This summary is machine-generated.

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Cutaneous malacoplakia, a rare condition, can develop secondary to Escherichia coli sepsis. Prompt antibiotic treatment effectively resolved both the skin lesions and the sepsis in a patient with multiorgan failure.

Area of Science:

  • Dermatology
  • Infectious Diseases
  • Pathology

Background:

  • Escherichia coli sepsis can lead to severe systemic complications, including multiorgan failure.
  • Cutaneous manifestations are uncommon but can occur in severe bacterial infections.
  • Malacoplakia is a rare inflammatory condition characterized by the presence of Michaelis-Guttmann bodies.

Observation:

  • A 69-year-old male presented with indurated, erythematous plaques on the left arm and flank.
  • The patient had a history of multiorgan failure secondary to Escherichia coli sepsis.
  • The clinical presentation suggested a possible cutaneous manifestation of the underlying infection.

Findings:

  • Cutaneous malacoplakia was diagnosed based on clinical and histopathological findings.

Related Experiment Videos

  • The patient received intravenous antibiotic therapy targeting Escherichia coli.
  • Resolution of both the cutaneous malacoplakia and the sepsis was observed following treatment.

    • Implications:

    • This case highlights a rare association between Escherichia coli sepsis and cutaneous malacoplakia.
    • Early diagnosis and appropriate antibiotic management are crucial for favorable outcomes in such cases.
    • Further research may elucidate the specific mechanisms linking E. coli sepsis to malacoplakia development.