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Updated: Jul 29, 2026
07:07
Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice
Published on: January 12, 2017
[Initial axonal degeneration in the pulp of deciduous teeth]
Zeitschrift Fur Mikroskopisch-Anatomische Forschung
|January 1, 1978
Summary
Early nerve fiber degeneration begins in the dental pulp of primary molars in young children (ages 4-5). This axonal degeneration affects the axolemma and internal organelles, particularly at contact sites with fibroblasts.
Area of Science:
- Neuroscience
- Pediatric Dentistry
- Cell Biology
Context:
- The study investigates early degenerative changes in nerve fibers within the dental pulp of deciduous molars.
- Focuses on children aged four to five years, a critical developmental period.
Purpose:
- To identify and characterize the initial stages of regressive processes affecting nerve fibers in primary teeth.
- To detail the specific axonal degenerative changes occurring at the cellular and subcellular levels.
Summary:
- Initial nerve fiber degeneration is observable in the dental pulp of deciduous molars in 4-5-year-old children.
- Degenerative changes are most pronounced at the interface between axons and fibroblasts.
- These changes involve both the axolemma and various organelles within the axoplasm.
Impact:
- Provides foundational knowledge on the timeline of neurodegeneration in primary dentition.
- Highlights the cellular mechanisms underlying early axonal damage in pediatric dental pulp.
- Contributes to understanding the biological basis of sensory changes in young children's teeth.
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