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Evaluation of monoclonal anti-glycophorin B as an unusual anti-S
1International Blood Group Reference Laboratory, SW Regional Transfusion Centre, Bristol, UK.
Transfusion
|April 1, 1994
Abstract
Background:
Monoclonal antibody 148 is a murine monoclonal anti-glycophorin B that preferentially reacts with S+ human red cells.
Study Design And Methods:
Serologic and immunochemical studies were performed using red cells with various phenotypes.
Results:
These studies reveal that this monoclonal antibody is unusual in that it fails to agglutinate S+ TSEN+ red cells and agglutinates S- St(a+) and S- Dantu+ red cells.
Conclusion:
These results allow the prediction of the glycophorin composition of GP.Hop (Mi.IV) red cells.