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Dermal toxicity of hexachlorocyclohexane and pirimiphos-methyl in female rats
R B Raizada1, M K Srivastava, R A Kaushal
1Pesticide Toxicology Laboratory, Industrial Toxicology Research Centre, Lucknow, India.
Veterinary and Human Toxicology
|April 1, 1994
Abstract:
Technical hexachlorocyclohexane (100 mg/kg/d) and pirimiphosmethyl EC 50 (250 mg/kg/d) given individually and in combination to female rats for 7, 15 or 30 d by skin application caused poisoning, pathomorphological changes in vital organs, and significant enzymatic changes in liver and serum. The changes produced by the 2 compounds in combination did not suggest potentiation at the tested dose levels.