Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hemoglobin function under extreme life conditions

M E Clementi1, S G Condò, M Castagnola

  • 1Department of Experimental Medicine and Biochemical Sciences, University of Rome Tor Vergata, Italy.

European Journal of Biochemistry
|July 15, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The human carotid atherosclerotic plaque: an observational review of histological scoring systems.

European review for medical and pharmacological sciences·2023
Same author

Expression of L1 Cell Adhesion Molecule (L1CAM) in extracellular vesicles in the human spinal cord during development.

European review for medical and pharmacological sciences·2022
Same author

Interindividual variability in L1CAM expression in the human kidney during development: are there implications for fetal programming of kidney diseases presenting in adulthood?

European review for medical and pharmacological sciences·2022
Same author

The role of fetal programming in human carcinogenesis - May the Barker hypothesis explain interindividual variability in susceptibility to cancer insurgence and progression?

European review for medical and pharmacological sciences·2022
Same author

Acyl-CoA binding protein (ACBP) is highly expressed in the developing human kidney.

European review for medical and pharmacological sciences·2022
Same author

Strong ACE-2 expression in the choroidal vessels: do high choroid plexuses serve as a gateway for SARS-CoV-2 infection on the human brain?

European review for medical and pharmacological sciences·2022
Same journal

Comparison of expression patterns and cell adhesion properties of the mouse biliary glycoproteins Bgp1 and Bgp2.

European journal of biochemistry·2020
Same journal

AB 3.1.1.1 (or EC 3.1.1.?).

European journal of biochemistry·2020
Same journal

Cdk5.

European journal of biochemistry·2018
Same journal

Structure of the core oligosaccharide of a rough-type lipopolysaccharide of Pseudomonas syringae pv. phaseolicola.

European journal of biochemistry·2004
Same journal

Monitoring ligand-mediated nuclear receptor-coregulator interactions by noncovalent mass spectrometry.

European journal of biochemistry·2004
Same journal

Solution structure of long neurotoxin NTX-1 from the venom of Naja naja oxiana by 2D-NMR spectroscopy.

European journal of biochemistry·2004
See all related articles

Hemoglobin

Area of Science:

  • Biochemistry
  • Physiology
  • Evolutionary Biology

Background:

  • Hemoglobin is crucial for oxygen transport in diverse species.
  • Hemoglobin function is vital under various environmental conditions.

Purpose of the Study:

  • To analyze the thermodynamics of oxygen binding in hemoglobins.
  • To reveal adaptive mechanisms in hemoglobin function across species.

Main Methods:

  • Thermodynamic analysis of oxygen binding.
  • Comparative study of hemoglobins from different species (e.g., fish, human fetus).

Main Results:

  • Identified adaptive mechanisms linked to heterotropic effectors and oxygen binding.
  • Demonstrated evolutionary alterations in heterotropic interactions.

Related Experiment Videos

  • Showcased optimization of the oxygenation-deoxygenation cycle based on physiological needs.

    • Conclusions:

    • Thermodynamic analysis provides deeper physiological insights than structural characterization alone.
    • Evolution optimizes hemoglobin function through structural modifications of heterotropic interactions.