[Early diagnosis of prostatic cancer]

Prostate cancer is the most common neoplasia in males and, since it is curable only when detected in the early stages, it was estimated that screening would detect tumours in curable stages which would enhance the results in the fight against the disease. This, however, has not been elucidated since the condition's natural history in many cases unknown and it may be that unnecessary and iatrogenic overtreatment is being induced. The paper analyzes the various tests and diagnostic procedures available, primarily digital rectal examination, PSA determination, and transrectal ultrasound all used individually and in combination. Several unknown aspects await to be answered and many long-term studies continue to be necessary to explain whether early diagnosis of asymptomatic disease and subsequent treatment can improve life expectancy and quality of life as compared to plain treatment of symptomatic cases. We hope the answer will be available shortly and that we are "able to diagnose cancer in time but treat it only when we know it is required.