[Examination in clinical course of HCV in interferon treatment]

We treated 812 patients who had chronic hepatitis C with interferon (IFN) and studied the effects of interferon. We defined complete response as normalization of amino-transferase more than 6 months after termination of IFN. Complete response by means of IFN therapy is dependent to some factors, that is HCV-genotype, quantity of HCV-RNA, histology. Cases of HCV genotype III or IV, CH2A, less than 10(5) copy/ml of HCV-RNA are effective in treatment of IFN. On the other hand, cases of HCV genotype II, CH2B, more than 10(6) copy/ml of HCV-RNA are effective in treatment of IFN.