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Large volume leukapheresis to maximize peripheral blood stem cell collection
1Department of Pathology, Emory University School of Medicine, Atlanta, GA 30322.
Journal of Hematotherapy
|January 1, 1993
Summary
Large volume leukapheresis, processing over three blood volumes, is safe and feasible across patient groups using various cell separators. This procedure
Area of Science:
- Hematology
- Medical Technology
- Clinical Procedures
Background:
- Leukapheresis is a medical procedure to remove white blood cells.
- Large volume leukapheresis involves processing >3 blood volumes in one session.
- The safety and efficacy of this procedure require detailed examination.
Purpose of the Study:
- To provide a comprehensive overview of large volume leukapheresis.
- To detail the history, techniques, and outcomes of the procedure.
- To discuss potential complications and future applications.
Main Methods:
- Review of existing literature and clinical data.
- Description of various cell separation technologies used.
- Analysis of patient outcomes and adverse events.
Main Results:
- Large volume leukapheresis is technically achievable and safe.
- Multiple cell separators are suitable for performing the procedure.
- The procedure can be applied to diverse patient populations.
Conclusions:
- Large volume leukapheresis is a safe and versatile procedure.
- Further research into its proposed uses is warranted.
- Standardization of techniques may enhance outcomes.