Related Experiment Videos
Suppression of in vivo tumor-induced angiogenesis by the protein-bound polysaccharide PSK
T Kanoh1, K Matsunaga, K Saito
1Kureha Chemical Ind. Co., Ltd., Biomedical Research Laboratories, Tokyo, Japan.
In Vivo (Athens, Greece)
|March 1, 1994
Abstract:
The anti-angiogenic effects of an antitumor protein-bound polysaccharide, PSK, obtained from cultured mycelia of Coriolus versicolor in basidiomycetes were examined by the mouse dorsal air sac assay. PSK suppressed the mouse hepatoma MH134-induced angiogenesis when assessed by morphological and biochemical examinations. This finding suggested that the anti-metastatic effect of PSK is attributed to the suppression of tumor-induced angiogenesis.