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Risk for ABR abnormalities in the nursery

A Salamy¹, L Eldredge

¹Department of Psychiatry, University of California, San Francisco.

Electroencephalography and Clinical Neurophysiology

|September 1, 1994

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Newborns exposed to cocaine in utero or with neurological issues face a higher risk of auditory brain-stem response (ABR) abnormalities. These findings highlight potential subtle neurological impacts persisting after birth.

Area of Science:

Neonatal neurology
Auditory neurophysiology

Background:

Auditory brain-stem response (ABR) is crucial for assessing hearing in newborns.
Identifying risk factors for ABR abnormalities is essential for early intervention.

Purpose of the Study:

To investigate the association between neonatal complications and auditory brain-stem response (ABR) abnormalities.
To determine the risk of ABR deviations in infants with specific newborn diagnoses.

Main Methods:

Review of records for 1087 full- and pre-term infants with normal hearing.
Classification of subjects based on common newborn complications.
Logistic regression analysis to assess the risk of ABR deviations.

Main Results:

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Infants with in utero cocaine exposure or neurological signs/brain anomalies were 4-5 times more likely to have deviant ABRs.

Synergistic effects of variables increased abnormal response risk based on gestational age and disorder type.

Conclusions:

Neonatal complications, particularly cocaine exposure and neurological issues, significantly increase the risk of ABR abnormalities.
Subtle neurological influences may persist in newborns at the time of discharge.