Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Biochemical markers in RA]

T M Hansen1

  • 1Reumatologisk afd, Københavns Amts Sygehus i Herlev.

Nordisk Medicin
|January 1, 1994
PubMed
Summary
This summary is machine-generated.

Acute-phase reactants like C-reactive protein (CRP) indicate inflammation. Measuring connective tissue markers aids in evaluating synovial inflammation and tissue destruction.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction: p73 and caspase-cleaved p73 fragments localize to mitochondria and augment TRAIL-induced apoptosis.

Oncogene·2025
Same author

Microstructural white matter brain abnormalities in patients with idiopathic fecal incontinence.

Neurogastroenterology and motility·2017
Same author

Cortical and spinal assessment - a comparative study using encephalography and the nociceptive withdrawal reflex.

Journal of pharmacological and toxicological methods·2016
Same author

Extracorporeal cardiopulmonary resuscitation after out-of-hospital cardiac arrest in a Danish health region.

Acta anaesthesiologica Scandinavica·2016
Same author

Fusobacterium necrophorum tonsillitis: an important cause of tonsillitis in adolescents and young adults.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2015
Same author

Functional reorganization of brain networks in patients with painful chronic pancreatitis.

European journal of pain (London, England)·2014
Same journal

[Nordisk Medicine 1929-1998. Thanks and farewell!].

Nordisk medicin·1999
Same journal

[Scientific fraud and misconduct--need for comprehensive terminology].

Nordisk medicin·1999
Same journal

[Labor-market for Scandinavian physicians in the year 2000--dearth or surplus?].

Nordisk medicin·1999
Same journal

[Internet in consultation--headed for trouble?].

Nordisk medicin·1999
Same journal

[Interpretation of questionnaires. An translation method problem].

Nordisk medicin·1999
Same journal

[Assessment of patients' health status--review of the literature and assessment methods].

Nordisk medicin·1999
See all related articles

Area of Science:

  • Biochemistry
  • Immunology
  • Rheumatology

Context:

  • Inflammation is often indicated by elevated plasma levels of acute-phase reactants.
  • C-reactive protein (CRP) is a sensitive and widely used marker for inflammation.
  • Erythrocyte sedimentation rate (ESR) increases with acute-phase reactants but can also be affected by other conditions like anemia.

Purpose:

  • To explore the utility of acute-phase reactants and connective tissue markers in assessing inflammatory conditions.
  • To highlight the role of C-reactive protein (CRP) as a key indicator of inflammation.
  • To discuss the diagnostic potential of measuring blood, synovial fluid, and urine markers for evaluating joint and bone health.

Summary:

  • Plasma concentrations of acute-phase reactants, notably C-reactive protein (CRP), typically rise during inflammatory activity.

Related Experiment Videos

  • While ESR also increases with inflammation, it can be elevated due to non-inflammatory factors such as hypergammaglobulinemia and anemia.
  • Analysis of connective tissue markers in biological samples offers novel methods for assessing synovial inflammation, pannus formation, and cartilage/bone degradation.

    • Impact:

    • Provides insights into biochemical markers for diagnosing and monitoring inflammatory diseases.
    • Enhances understanding of the diagnostic value of CRP and ESR in clinical practice.
    • Opens avenues for improved evaluation of joint pathologies and tissue damage through advanced marker analysis.