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Pancreatic enzyme elevations after blunt trauma

S Ryan1, A Sandler, S Trenhaile

  • 1Department of Surgery, University of Iowa College of Medicine, Iowa City.

Surgery
|October 1, 1994
PubMed
Summary
This summary is machine-generated.

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Blunt trauma patients frequently show elevated pancreatic enzymes (amylase and lipase), but most remain asymptomatic. Retroperitoneal injury may indicate a risk for developing pancreatitis.

Area of Science:

  • Trauma surgery
  • Gastroenterology
  • Critical care medicine

Background:

  • Elevated pancreatic enzymes (amylase and lipase) are common post-trauma.
  • Blunt trauma patients often exhibit these enzyme elevations.

Purpose of the Study:

  • To investigate the incidence of pancreatic enzyme elevations after blunt trauma.
  • To understand the natural history and relationship to posttraumatic pancreatitis.

Main Methods:

  • Prospective study of 100 trauma patients in surgical ICU.
  • Daily serum amylase and lipase measurements.
  • Enrolled patients with elevated enzymes after 3 days for further monitoring.

Main Results:

  • 17% of patients had persistent pancreatic enzyme elevations.

Related Experiment Videos

  • These patients had higher Injury Severity Scores, hypotension, and severe head injuries.
  • 5% developed clinical pancreatitis, often associated with lumbar spine or retroperitoneal injuries.

    • Conclusions:

    • 17% of blunt trauma patients experience persistent pancreatic enzyme elevations, mostly asymptomatic.
    • Retroperitoneal injury is a potential risk factor for pancreatitis.
    • Enteral feeding is safe for patients with isolated head injuries.