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Exposure of CHO cells to AluI: comparison of chromosomal aberrations and cell survival
G Obe1, P Eke, C Johannes
1University GH Essen, Department of Genetics, Germany.
Mutation Research
|February 1, 1995
Abstract:
Chinese hamster ovary (CHO) cells were exposed to various doses of the restriction endonuclease AluI in the presence of 2.2 M glycerol. Some of the cells were cultured for analysis of chromosomal aberrations and some for analysis of colony-forming ability. Cell killing is mainly mediated by chromosomal aberrations.