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A previously unidentified choline acetyltransferase transcript in the human foetal brain
M Schmitt1, J M Garnier, P Simoni
1Laboratoire de génétique moléculaire des eucaryotes, CNRS, U184 INSERM, Faculté de Médecine, Strasbourg, France.
Neuroscience Letters
|September 12, 1994
Abstract:
To identify choline acetyltransferase (ChAT) transcript(s) in human foetal brain we used the reverse polymerase chain reaction including different couples of oligonucleotide primers. The analysis indicated the presence of a new choline acetyltransferase transcript containing at its 5' end an untranslated exon (E1A) of 57 nucleotides in length extending from Nt 3771 to Nt 3828. It differs in the 5'-non coding region from the M-N-R type mRNA previously described in mouse and rat.