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Effect of contignasterol on histamine release induced by anti-immunoglobulin E from rat peritoneal mast cells
M Takei1, D L Burgoyne, R J Andersen
1Forschungsinstitut Borstel, Germany.
Journal of Pharmaceutical Sciences
|September 1, 1994
Abstract:
In rat peritoneal mass cells induced by anti-immunoglobulin E (anti-IgE), contignasterol (1) inhibited histamine release in a dose-dependent manner. On the other hand, a reduction product of contignasterol (2) did not inhibit histamine release from mast cells induced by anti-IgE.