Effect of electrochemical therapy on immune functions of normal and tumour-bearing mice

The effect of electrochemical therapy (ECT) on immune functions of normal and tumour-bearing mice was studied. In normal mice, ECT had no obvious effect on delayed type hypersensitivity (DTH) or on the mononuclear phagocytic system, but significantly reduced the production of agglutinin antibodies. In tumour-bearing mice, ECT enhanced the DTH reaction, increased the production of agglutinin antibodies and enhanced the clearance of Congo red. In conclusion, in tumour-bearing mice, ECT enhanced both cellular immune functions of T- and B-lymphocytes and non-specific immune functions of the phagocytic system.