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[Palliative surgery in nonresectable pancreatic carcinoma]
D Guglielminetti1, M Burgini, G Gaddoni
1Ospedale S. Maria delle Croci, Seconda Divisione Chirurgica, Regione Emilia Romagna U.S.L. 35, Ravenna.
Il Giornale Di Chirurgia
|October 1, 1994
Summary
Palliative surgery for adenocarcinoma of the pancreas effectively manages biliary and duodenal obstruction. This approach is beneficial for patients without distant metastases, aiding in tumor evaluation for potential resection.
Area of Science:
- Gastroenterology
- Surgical Oncology
Context:
- Presents findings from 30 cases of pancreatic adenocarcinoma treated surgically.
- Focuses on palliative surgical interventions between 1985-1991 at S. Maria delle Croci Hospital.
Purpose:
- To evaluate the efficacy and outcomes of palliative surgery for pancreatic adenocarcinoma.
- To determine the utility of surgical palliation in managing obstructive symptoms and for tumor staging.
Summary:
- 30 patients with pancreatic adenocarcinoma underwent palliative surgery (biliary bypass or gastroenterostomy) for jaundice and duodenal obstruction.
- Tumors were predominantly Stage 3 (60%). Mean hospitalization was 15 days, with 6.6% perioperative mortality and 6.5 months mean survival.
- Palliative surgery is indicated for neoplastic stenosis without liver/lung metastases and when histological evaluation is needed for resection assessment.
Impact:
- Highlights the role of palliative surgery in improving quality of life for advanced pancreatic cancer patients.
- Provides data on perioperative mortality and survival rates for this specific surgical approach.
- Informs clinical decision-making regarding surgical palliation versus other treatment modalities.