Reprocessing and multiple use of hemodialyzers: a critical appraisal

Economic considerations have made the reuse of hemodialyzers desirable, particularly with the introduction of expensive devices, such as large surface area or high-flux dialyzers, hemodiafilters and hemofilters. Recent studies have shown that certain reprocessing techniques confer improved biological properties on dialyzers compared with new membranes. Several investigators observed certain symptoms which occurred with greater frequency in patients receiving first use dialyzers as opposed to patients receiving dialysis treatment with reused dialyzers. Despite the potential advantages of more biocompatible membranes, and less expensive dialyzers, the safety and efficiency of reuse is the subject of some controversy. The article critically reviews the available scientific information on the risks and benefits of reprocessing.