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Updated: Aug 18, 2026

A Cell Free Assay System Estimating the Neutralizing Capacity of GM-CSF Antibody using Recombinant Soluble GM-CSF Receptor
Published on: June 27, 2011
The international standard for granulocyte colony stimulating factor (G-CSF). Evaluation in an international
A R Mire-Sluis1, R G Das, R Thorpe
1Division of Immunobiology, National Institute for Biological Standards and Control, Potters Bar, Herts, UK.
Abstract:
Three ampouled preparations of granulocyte colony stimulating factor (G-CSF) have been evaluated by 29 laboratories in 11 countries for their suitability to serve as international standards for these materials. The preparations were assayed in a wide range of in vitro bioassays and immunoassays. On the basis of results reported here with the agreement of the participants in the study and with the authorisation of the Expert Committee on Biological Standardization (ECBS) of the World Health Organization (WHO) one of the preparations (88/502) was established as the international standard for G-CSF.
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