SH2 and SH3 domains in signal transduction

SYK interaction with ITGβ4 suppressed by Epstein-Barr virus LMP2A modulates migration and invasion of nasopharyngeal carcinoma cells.

Oncogene·2014

The ShcA adaptor activates AKT signaling to potentiate breast tumor angiogenesis by stimulating VEGF mRNA translation in a 4E-BP-dependent manner.

Oncogene·2014

The ShcA SH2 domain engages a 14-3-3/PI3'K signaling complex and promotes breast cancer cell survival.

Oncogene·2012

Generating a panel of highly specific antibodies to 20 human SH2 domains by phage display.

Protein engineering, design & selection : PEDS·2010

EphB2 and EphA4 receptors regulate formation of the principal inter-hemispheric tracts of the mammalian forebrain.

Neuroscience·2009

Effects of dasatinib on EphA2 receptor tyrosine kinase activity and downstream signalling in pancreatic cancer.

British journal of cancer·2008

Cancer immunotherapy with oncolytic myxoma virus.

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Operation oncolysis: Reoviruses in the theater of cancer war.

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AAV vectors for cancer gene therapy.

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Advances in cancer research·2026

Electron-withdrawing group effects on the structural, electronic, reactivity, and binding characteristics of triazolopyrimidine herbicides: a comparative study of diclosulam, cloransulam-methyl, and cloransulam.

RSC advances·2026

Multiple binding modes underlie Cannabis sativa cannabinoids recognition by peroxisome proliferator-activated receptor gamma.

Frontiers in bioinformatics·2026

Sulfonamide-Based 2-Amino-1,3,4-Oxadiazole Derivatives as Dual Cholinesterase and Carbonic Anhydrase Inhibitors: Design, Synthesis, Kinetic Characterization, Molecular Modeling, and ADMET Evaluation.

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Revisiting multicomponent Doebner and Povarov quinoline synthesis for modern-day drug-discovery.

Organic & biomolecular chemistry·2026

Salvinorin A in humans: A systematic review of pharmacokinetics, pharmacodynamics, and safety.

Journal of psychopharmacology (Oxford, England)·2026

Organic photosensitizers for antifungal therapy: structural diversity and emerging applications.

Chemical communications (Cambridge, England)·2026

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SH2 and SH3 domains in signal transduction

Related Concept Videos

SYK interaction with ITGβ4 suppressed by Epstein-Barr virus LMP2A modulates migration and invasion of nasopharyngeal carcinoma cells.

The ShcA adaptor activates AKT signaling to potentiate breast tumor angiogenesis by stimulating VEGF mRNA translation in a 4E-BP-dependent manner.

The ShcA SH2 domain engages a 14-3-3/PI3'K signaling complex and promotes breast cancer cell survival.

Generating a panel of highly specific antibodies to 20 human SH2 domains by phage display.

EphB2 and EphA4 receptors regulate formation of the principal inter-hemispheric tracts of the mammalian forebrain.

Effects of dasatinib on EphA2 receptor tyrosine kinase activity and downstream signalling in pancreatic cancer.

Cancer immunotherapy with oncolytic myxoma virus.

Cancer terminator viruses: Unique conditionally replication competent oncolytic viruses producing therapeutic anti-cancer immunomodulating agents.

Advancing clinical translation of oncolytic adenoviruses.

Operation oncolysis: Reoviruses in the theater of cancer war.

AAV vectors for cancer gene therapy.

Vesicular stomatitis virus (VSV) as an oncolytic therapeutic agent for cancer.

Electron-withdrawing group effects on the structural, electronic, reactivity, and binding characteristics of triazolopyrimidine herbicides: a comparative study of diclosulam, cloransulam-methyl, and cloransulam.

Multiple binding modes underlie Cannabis sativa cannabinoids recognition by peroxisome proliferator-activated receptor gamma.

Sulfonamide-Based 2-Amino-1,3,4-Oxadiazole Derivatives as Dual Cholinesterase and Carbonic Anhydrase Inhibitors: Design, Synthesis, Kinetic Characterization, Molecular Modeling, and ADMET Evaluation.

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SH2 and SH3 domains in signal transduction

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