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Assessment of Yqh translocations
J L Fernández1, S Pereira, A Campos
1Centro Oncológico de Galicia, Laboratorio de Genética, La Coruña, Spain.
Journal of Medical Genetics
|December 1, 1994
Abstract:
Two initially presumed Yqh translocations, one to Xp and another to 21p, were assessed by conventional banding procedures, 5-azacytidine treatment, electron microscopy, and fluorescence in situ hybridisation. While the Yqh nature of the heterochromatic block from Xp was confirmed, this was not the case with the 21ph+ variant. In conclusion, conventional banding techniques are insufficient to diagnose Y;G translocations.