Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Allergy to ingested cereals in atopic children

L Räsänen1, M Lehto, K Turjanmaa

  • 1Department of Clinical Medicine, University of Tampere, Finland.

Allergy
|December 1, 1994
PubMed
Summary

This study investigated cereal allergy in children with atopic dermatitis (AD). Combining immediate and delayed hypersensitivity tests reliably diagnosed cereal allergy, distinguishing it from celiac disease.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of an X-ray scatter mobile application on radiation protection training: A user experience study.

Radiography (London, England : 1995)·2026
Same author

Empowerment and mobile technology in the detection and treatment of main cardiovascular risk factors of patients with ischemic stroke or transient ischemic attack: a protocol for a multicenter randomized controlled trial (CARDIOSTROKE).

Trials·2025
Same author

Use of primary health care services and mortality in older patients with type 2 diabetes with or without comorbidities.

Scandinavian journal of primary health care·2023
Same author

The association between bacterial infections and the risk of coronary heart disease in type 1 diabetes.

Journal of internal medicine·2020
Same author

Nasal mucosa and blood cell transcriptome profiles do not reflect respiratory symptoms associated with moisture damage.

Indoor air·2018
Same author

A novel glycocluster molecule prevents timothy-induced allergic airway inflammation in mice.

Allergy·2018

Area of Science:

  • Pediatric Allergy and Immunology
  • Gastroenterology
  • Dermatology

Background:

  • Atopic dermatitis (AD) in children can be associated with various hypersensitivities.
  • Accurate diagnosis of cereal allergy or intolerance is crucial for effective management.

Purpose of the Study:

  • To investigate clinical features, hypersensitivity mechanisms, and differential diagnosis of cereal allergy or intolerance in children with AD.
  • To evaluate diagnostic methods for cereal allergy.

Main Methods:

  • Oral provocation tests were used to identify reactions to specific cereals (wheat, rye, barley, oats).
  • Type I allergy tests (prick test, RAST, histamine-release test), patch tests, and lymphocyte proliferation tests were employed.
  • Antibody levels (IgE, IgA, IgG) against gliadin and HLA-DR3 status were assessed.

Related Experiment Videos

Main Results:

  • 18 children reacted to wheat, 3 to rye, 1 to barley, and 1 to oats upon oral provocation.
  • Symptoms included dermatologic, gastrointestinal, or oropharyngeal reactions with immediate, delayed, or dual onset.
  • A combination of allergy tests detected most immediate and delayed reactors, with additional tests identifying remaining cases.
  • Elevated gliadin antibodies were common, but celiac disease markers were rare.

Conclusions:

  • Combining immediate and delayed hypersensitivity testing provides a reliable method for diagnosing cereal allergy in children with AD.
  • Cereal allergy and celiac disease appear to be distinct conditions and rarely coexist.