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Related Experiment Videos

Biliary sludging in critically ill trauma patients

B Toursarkissian1, P A Kearney, D T Holley

  • 1Division of General Surgery, University of Kentucky Chandler Medical Center, Lexington 40536-0084, USA.

Southern Medical Journal
|April 1, 1995
PubMed
Summary

Critically ill trauma patients frequently develop gallbladder sludge, particularly those requiring transfusions. This sludge may be linked to complications like cholecystitis and pancreatitis.

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Area of Science:

  • Gastroenterology
  • Trauma Surgery
  • Critical Care Medicine

Background:

  • Gallbladder sludge is a common issue in hospitalized patients.
  • Its development in critically ill trauma patients is not well understood.
  • Early detection and understanding risk factors are crucial for patient outcomes.

Purpose of the Study:

  • To prospectively investigate the incidence of gallbladder sludge in critically ill trauma patients.
  • To identify potential risk factors and clinical associations with sludge formation.
  • To assess the relationship between gallbladder sludge and pancreatobiliary complications.

Main Methods:

  • Serial weekly ultrasonography was used to screen 19 critically ill trauma patients.
  • Data on transfusion requirements, laboratory findings, and injury severity scores were collected.

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  • Clinical outcomes, including complications and feeding methods (enteral vs. total parenteral nutrition), were monitored.

    • Main Results:

    • Gallbladder sludge developed in 14 out of 19 patients during hospitalization.
    • Sludge formation was significantly associated with increased transfusion requirements.
    • Enteral nutrition did not prevent sludge; all patients on total parenteral nutrition developed sludge. Three patients experienced complications possibly related to sludge.

    Conclusions:

    • Gallbladder sludge is a frequent complication in critically ill trauma patients.
    • Increased transfusion requirements may be a risk factor for sludge development.
    • Gallbladder sludge may be associated with pancreatobiliary complications in this patient population.