Related Experiment Videos
The neuroanatomical specificity of ethanol action on ligand-gated ion channels: a hypothesis
G R Breese1, A L Morrow, P E Simson
1Brain and Development Research Center, University of North Carolina at Chapel Hill 27599, USA.
Alcohol and Alcoholism (Oxford, Oxfordshire). Supplement
|January 1, 1993
Abstract:
The studies described will demonstrate that the subunit composition of a GABAA receptor allows ethanol to enhance responses to GABA. Since we have determined that ethanol will influence responses to glycine, nicotine and NMDA in some, but not all, neurons with receptors to these agonists, we hypothesize that specific receptor subtypes of these ligand-gated ion channels will be affected by ethanol.