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Antibody-induced alterations of protein and nucleic acid metabolism during experimental thyroglobulin immunization
1Department of Animal Physiology, Bose Institute, Calcutta, India.
Methods and Findings in Experimental and Clinical Pharmacology
|October 1, 1994
Abstract:
The protein and nucleic acid contents of liver, spleen, muscle, kidney, and brain were studied in experimental autoimmune thyroiditis. Protein and ribonucleic acid levels showed a positive increase in the case of liver, spleen, and muscle on days 56 and 98 after immunization and on day 147 they reached control levels. Spleen deoxyribonucleic acid showed a significant increase on day 56, whereas the other days showed no change. Kidney and brain tissue revealed no change.