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Intrapleural mitoxantrone for the palliative treatment of malignant pleural effusions
1Department of Medicine, Hospital Nuestra Señora de la Candelaria, Santa Cruz de Tenerife, Canary Islands, Spain.
Abstract:
A group of 21 patients with malignant pleural effusions were treated with the instillation of 40 mg mitoxantrone intrapleurally, after complete fluid drainage. There was a 100% complete response rate with no toxic effects (0%). The mean survival of the patients was 57.1 weeks.